Top Healthcare Companies by Revenue 2026

Amgen (AMGN) reported $33.4B revenue in FY2024, up 19% YoY (post-Horizon acquisition). Top-5 global biotech. 10+ blockbuster drugs. ~24,000 employees. HQ: Thousand Oaks, CA. Market cap ~$130B.

$1.7B annual revenue; 160K+ providers, 117M patients; 18.15% EHR market share; 6,713+ companies using 2025; acquired by Bain Capital & Hellman & Friedman Nov 2021 at $17B; AI interoperability 2025

$2.56B revenue 2024; Q2 2025 $631.9M (-1.6% YoY); 101-103M projected US members 2025; telehealth market leader; telehealth market $123.26B 2024 to $455.27B 2030; 46.58% North America share

UnitedHealth Group (NYSE: UNH) health services at $226B revenue combining Optum Health clinics, Optum Rx PBM for 65M+, and Change Healthcare analytics; largest US health services company competing with CVS/Caremark.

Community hospital EHR serving 2,300 organizations; privately held 55-year-old MEDITECH competing with Epic on value with cloud-native Expanse platform and AI documentation.

Rebranded to Veradigm Jan 2023; $620-635M revenue expected 2024; 180K+ physician users; 3.6% ambulatory EHR market share; sold hospital business to Harris Computer $700M 2022; Nasdaq suspended Feb 2024

B2B telehealth infrastructure for health systems with $275M revenue; white-label digital care platform with AI Automated Care Programs for chronic disease management.

$307M revenue 2024 (up from $296M 2023); $316M TTM Jun 2025; $26M adjusted EBITDA; 100M+ patient records; expects double-digit growth 2025; low-20s net new platform clients 2024; healthcare analytics leader

Practice management platform for 130K independent physicians from Kareo+PatientPop merger; EHR, billing, and patient acquisition marketing for small practices competing with athenahealth.

Healthcare data company with 130K connected physicians; EHR-connected real-world evidence network for pharma analytics rebranded from Allscripts competing with IQVIA for life sciences data.

Major ambulatory EHR serving 150K providers bootstrapped to scale; Sunoh.ai ambient clinical documentation and revenue cycle management competing with Epic and athenahealth for practices.

Healthcare clearinghouse processing 15B+ annual claims acquired by Optum; 2024 ransomware attack caused $1B+ provider disruption and sparked nationwide healthcare cybersecurity overhaul.

Modern cloud-native EHR for direct primary care and value-based care organizations; API-first architecture replacing legacy systems competing with athenahealth and Elation Health.

Kroger-owned in-store pharmacy chain with 2,200 locations in supermarket banners; prescription services integrated with grocery loyalty program competing with CVS and Walgreens.

Ambulatory EHR platform serving 155K providers taken private by Thoma Bravo for $1.8B; behavioral health specialty depth and AI clinical documentation modernization.

SF healthcare tech with remote patient monitoring devices and AI medical billing for CCM/RPM programs; $132M General Catalyst and Sequoia backed generating $200-300/month per patient in additional practice revenue.

NYSE: COST | $2.6B Rx revenue 2024 (11th largest US pharmacy); 19%+ prescription growth; below-market drug pricing open to non-members in most states; no PBM markup model

San Francisco primary care EHR for independent and DPC practices with physician-first clinical workflow design; $50M+ backed competing with athenahealth for 35,000+ independent primary care providers.

Walmart-owned warehouse club pharmacy with 500+ locations; bulk purchasing enables discounted $4/$10 generics competing with Costco Pharmacy as part of Walmart's health services strategy.

$200M funding 2025; $200M+ ARR (doubled 3 consecutive years); $6B valuation (merged Athelas); 130+ health systems; HCA partnership; acquired Augmedix $139M/Memora; healthcare RCM leader

Patient engagement platform with automated SMS reminders, self-scheduling, and EHR integration for health systems; $130M+ a16z-backed competing with Phreesia for healthcare communication automation.

NASDAQ-listed (GDRX) prescription savings platform comparing prices across 70K+ pharmacies; $750M revenue with stock under pressure from Amazon Pharmacy and Cost Plus Drugs competition.

NYSE-listed (PHR) patient intake platform digitizing check-in for 4,000+ practices at $383M revenue; pharma-funded activation programs competing with Epic and Clearwave for healthcare front-office engagement.

1M+ clinicians 150+ countries; 250K active providers; $50.2M revenue; acquired Telehealth.org/TeleMental Health Institute 2025; TIME HealthTech 2025; Ventures fund; telemedicine leader

Merged with PatientPop → Tebra 2021; $222M funding; $1B+ valuation; $72M 2023 (Golub); 100K providers; 90M patients; 1,000 employees; practice management/EHR leader

B2B digital pharmacy infrastructure acquired by LetsGetChecked for $525M in Aug 2024; processed 1M+ prescriptions; $322M total funding;

San Jose clear aligner orthodontics inventor (NASDAQ: ALGN) at $3.23B 2024 revenue; 20 million Invisalign patient milestone Q1 2025 across 280,000+ doctors with iTero Lumina scanner competing with 3M Clarity for orthodontic clear aligner prescript...

Boston AI GPCR drug discovery with $1.3B Eli Lilly collaboration Aug 2025 for obesity/cardiometabolic; $158M total ($120M RA Capital/Insight/NVIDIA/Lilly Series A Sep 2024) with MC4R obesity program advancing to IND competing with Relay Therapeutics.

Largest US pharmacy chain with ~9,000 locations; expanding pharmacy-only format in 2026; parent CVS Health also operates Aetna (health insurance) and Caremark (PBM), creating a vertically integrated healthcare mega-platform from pharmacy to insura...

SF YC W21 AI patient education for thyroid and chronic conditions at $125M valuation Sep 2024; $22.2M from Google, Harvard endowment, Gaingels/YC competing with Paloma Health for AI-driven medical knowledge accessibility for underdiagnosed chronic...

US YC S23 at-home 30-minute cancer screening for prostate, bladder, and ovarian cancers; $846K Mayo Clinic/TQ Ventures/YC-backed with synthetic biology + computer vision from Oxford Rhodes Scholar founders competing with GRAIL for accessible early...

SF YC Stanford AI Lab spinout healthcare automation at General Catalyst/Telesoft-backed; AI agents trained on millions of clinical data points automating prior authorization and document-to-EHR extraction for Fortune 500 providers competing with C...

US MRI microstructure imaging algorithm (FDA-cleared July 2024) adding higher resolution to existing scanners projecting $2M additional annual revenue per scanner; YC $1.49M competing with Subtle Medical and Siemens AI-Rad Companion for radiology AI.

Vienna Austria YC W21 desktop DNA synthesizer enabling on-demand oligo production in research labs at $3.1M revenue 2024; $1.99M BioTools Innovator-backed "Nespresso for DNA" at $35.5-49.5K competing with IDT and Evonetix for benchtop DNA synthesis.

Minnetonka US largest healthcare company (NYSE: UNH) at $400.3B 2024 revenue with UnitedHealthcare + Optum; 2025 leadership transition (Hemsley return, Witty departure) and suspended outlook after Change Healthcare breach and elevated medical costs.

Cambridge MA YC W20 nonprofit FMT distributor that served 1,000+ hospitals for C. diff treatment; suspended distribution Dec 2024 after FDA enforcement discretion ended; submitted IND Phase 2 Nov 2024 — microbiome therapeutics regulatory transition.

German AI startup won AI+MUNICH grant; digitizes patient admission and care planning for nursing facilities; AI-native platform reducing administrative time by up to 80% so care staff can spend more time on direct patient care rather than paperwork.

Chicago virtual care for ALS, Alzheimer's, and Parkinson's patients across 50 states; YC $46.3M B Capital/Google Ventures/CommonSpirit-backed as CMS GUIDE dementia provider competing with specialty neurology for neurodegenerative disease management.

US YC W21 protein conjugation technology for homogeneous ADCs and biologics at $9.1M total ($2.35M seed May 2024 LongeVC/Caffeinated) and $750K revenue Jun 2025; MPC platform competing with Ajinomoto and Abzena for precise ADC conjugation services.

Neptune Medical develops the Pathfinder endoscopy platform using Dynamic Rigidization technology, allowing flexible endoscopes to become rigid on demand for improved procedural control; FDA-cleared; targeting colonoscopy and small bowel procedures;

Harrison.ai is an Australian healthcare AI company building clinical-grade AI for radiology and pathology diagnostics; raised $129M+ AUD total at a $400M AUD valuation; its Annalise.ai radiology platform has FDA clearance and processes 5M+ studies;

HarmonyCares delivers home-based primary care to medically complex patients through a value-based model; serves 40,000+ patients in 15+ states; offers primary care, home health, hospice, palliative care, and diagnostic services under one clinical.

SF AI neurotherapeutics discovery platform for epilepsy/autism/Parkinson's with multimodal neural AI; animal lab + proof-of-concept + 2 patents in 1.5 months; $25M Philippines lab investment competing with Recursion for AI-driven CNS gene therapy.

Flo Health is the world's most downloaded women's health app with 70M+ monthly active users; raised $200M Series C in 2023 at a $800M valuation; offers AI-powered period tracking, fertility prediction, pregnancy monitoring, and menopause support;

SF YC W20 preclinical gene therapy for polycystic kidney disease (600K US patients) using AI-driven target identification; $1.1M raised with NIH SBIR grant, raising $4M seed competing with CRISPR Therapeutics for curative kidney genetic medicine.

Soda Health is a healthcare technology platform managing supplemental benefits (OTC, food, fitness, flex cards) for Medicare Advantage and Medicaid members; bridges health plan payments with retail and service providers to reduce health inequity;

Curative is an AI-powered health insurance plan for employers that eliminates copays and deductibles; raised $153M Series B at $1B valuation; partners with employers to offer zero-cost primary and specialist care using a curated provider network.