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Tempus(TEM (Nasdaq))

Leader

Publicly traded AI precision medicine company (Nasdaq: TEM); $1.27B revenue in 2025 (+83% YoY); $14B+ market cap; genomic profiling, algorithmic diagnostics, and clinical trial matching across oncology, neurology, and cardiology.

Best for: AI-Enabled Precision MedicineMarket leader
Life Sciences & BioTechAI-Enabled Precision MedicineTEM (Nasdaq)WebsiteUpdated May 2026

Company Overview

About Tempus

Tempus AI is a technology company applying artificial intelligence to advance precision medicine across oncology, neurology, psychiatry, and cardiology. Founded in 2015 by Eric Lefkofsky (co-founder of Groupon) and headquartered in Chicago, Illinois, Tempus built the world's largest library of clinical and molecular data and applies AI to help physicians make more personalized, data-driven treatment decisions. The company's core offerings include genomic profiling (sequencing tumor DNA to identify mutations and actionable targets), algorithmic diagnostic tests (AI-driven companion diagnostics for cancer treatment selection), clinical trial matching (connecting eligible patients to appropriate studies), and data licensing to pharmaceutical and biotech partners for drug discovery and clinical development.

Business Model & Competitive Advantage

Tempus went public on Nasdaq in June 2024 under the ticker symbol TEM, making its capital markets debut as one of the most anticipated healthcare AI IPOs of the year. In full-year 2025, Tempus reported revenue of $1.27B, an 83% increase from $693M in 2024, and achieved a record total contract value exceeding $1.1 billion. The company's market capitalization exceeds $14B, and Tempus stock rose 87% in 2025. Tempus provides 2026 revenue guidance of approximately $1.59B, representing ~25% growth. The company's genomics segment (lab testing revenue) and data and services segment (AI-powered analytics and pharma partnerships) both contribute to the top line, with the data segment expanding rapidly as pharmaceutical companies license Tempus's multimodal dataset for drug development applications.

Competitive Landscape 2025–2026

Tempus's competitive moat rests on the scale and quality of its proprietary dataset — covering millions of de-identified patient records with linked clinical, genomic, imaging, and outcomes data. This dataset, continuously enriched through clinical partnerships with health systems nationwide, underpins AI model training that competitors cannot easily replicate. Tempus competes with Foundation Medicine (Roche), Guardant Health, and NeoGenomics in genomic profiling, and with Flatiron Health (Roche) in real-world data for pharma, but its integrated AI platform spanning multiple disease areas differentiates its offering.

Founded
2015
Headquarters
Chicago, Illinois
Revenue
$1.27B
Curated content • Fact-checked and verified

Key Differentiators

Market Leader

Tempus is recognized as a market leader in the Life Sciences & BioTech sector, demonstrating strong industry presence and customer trust.

Enterprise Scale

With $1.27B in revenue, Tempus operates at enterprise scale with proven market validation.

Frequently Asked Questions

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