Stipple Bio

Challenger

Raised $100M oversubscribed Series A (Apr 2026) co-led by RA Capital and a16z Bio. Novel ADC platform targeting tumor-specific epitopes.

Precision Oncology
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Updated April 2026

Company Overview

About Stipple Bio

Stipple Bio is a precision oncology company that emerged from stealth in April 2026 with a $100 million oversubscribed Series A. The round was co-led by RA Capital Management, Andreessen Horowitz Bio+Health, and Nextech, with additional participation from GV and Emerson Collective — a top-tier syndicate that signals strong scientific conviction in the platform.

Business Model & Competitive Advantage

The company's "Pointillist" platform identifies tumor-specific cell surface epitopes for antibody-drug conjugates (ADCs), taking a differentiated approach in one of oncology's most competitive and capital-intensive therapeutic categories. While the ADC field has become crowded following the success of drugs like Enhertu, Stipple's approach focuses on discovering novel epitopes that existing ADCs cannot access, creating a potential source of first-in-class assets.

Competitive Landscape 2025–2026

Stipple's lead asset, STP-100, is targeted to enter clinical studies in 2027. The company's oversubscribed round in the current biotech funding environment is a strong signal of scientific credibility. With backing from investors who collectively represent hundreds of oncology investments, Stipple enters the clinic with a well-resourced balance sheet and strategic relationships across the oncology ecosystem.

Revenue
$100M
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Key Differentiators

Strong Challenger

Stipple Bio is an established challenger with significant market presence and competitive offerings in BioTech.

Growth Stage

Stipple Bio has achieved $100M in revenue, demonstrating strong product-market fit.

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