Be Biopharma logo

Be Biopharma

Emerging

$274M total raised including $92M Series C with Bristol Myers Squibb. Phase 1/2 active for BE-101 in Hemophilia B. CRISPR-engineered B cells as continuous protein factories.

Best for: Engineered B Cell TherapyEmerging, rapid growth
35
AI Score
Grade D
AI Visibility Score (Beta)
Life Sciences & BioTechEngineered B Cell TherapyWebsiteUpdated October 2026

Brand Intelligence Graph

Capabilities
Engineered B Cell Therapy

Company Overview

About Be Biopharma

Be Biopharma uses CRISPR to engineer a patient's own B cells into continuous protein-secreting factories — a one-time treatment designed to replace lifelong enzyme replacement therapy for rare metabolic diseases. The company has raised $274 million in total financing including a $92 million Series C co-led by Nextech Invest and Bristol Myers Squibb, with ARCH Venture Partners as a continuing investor, and has an active Phase 1/2 trial (BeCoMe-9) for BE-101 in Hemophilia B.

Business Model & Competitive Advantage

B cells are uniquely suited for this approach: they naturally produce antibodies in large quantities, are long-lived in vivo, and can be engineered ex vivo without the viral vector constraints of other gene therapy approaches. By replacing the B cell's antibody-producing program with a therapeutic protein payload via CRISPR, Be Bio creates a personalized, long-duration protein delivery system that the patient's own immune architecture sustains.

Competitive Landscape 2025–2026

Bristol Myers Squibb's co-investment is the most significant commercial signal: BMS has one of the world's largest rare disease and hematology portfolios, and its investment thesis is likely rooted in the platform's potential to replace BMS's existing enzyme replacement therapy products with a one-time cure approach. Hemophilia B data from the Phase 1/2 trial in 2026 will be the first human validation of engineered B cell protein secretion durability.

Curated content • Fact-checked and verified

Key Differentiators

Emerging Innovator

Be Biopharma is an emerging player bringing innovative solutions to the BioTech market.

Frequently Asked Questions

Estimated Visibility Trend (Beta)

Simulated 8-week rolling score

35
→ Stable

Based on estimated brand signals. Historical tracking coming soon.

Similar Brands

Emulate logo

Emulate

Life Sciences & BioTech
HealthtechB2bEnterpriseAi PoweredHardwarePlatformStartupScaleupGlobalNorth America

Emulate, Inc. is a Boston-based biotechnology company that designs, manufactures, and commercializes Organ-Chip technology — micro-engineered devices lined with living human cells that replicate the m

ConcertAI logo

ConcertAI

Life Sciences & BioTech
HealthtechAi PoweredAnalyticsB2bSaasEnterpriseData WarehousePlatformUnicorn

ConcertAI is a Boston-based company that combines artificial intelligence with real-world oncology data to accelerate cancer drug development and improve patient outcomes. Its platform integrates mult

DNAnexus logo

DNAnexus

Life Sciences & BioTech
B2bSaasHealthtechCloud NativeAnalyticsEnterprisePlatformGlobalAi PoweredInfrastructure

DNAnexus is the category-defining cloud platform for precision health data management, analysis, and collaboration. Founded in 2009 and headquartered in Mountain View, California, DNAnexus provides a

Saluda Medical logo

Saluda Medical

Life Sciences & BioTech
HealthtechHardwareB2bGlobalStartupAi Powered

Saluda Medical is a commercial-stage medical device company that has pioneered closed-loop neuromodulation therapy for chronic pain management. Headquartered in Macquarie Park, Australia (with US oper

Tempus logo

Tempus

Life Sciences & BioTech
HealthtechB2bAi PoweredAnalyticsPlatformPublicSaasTechnologyNorth America

Tempus AI is a technology company applying artificial intelligence to advance precision medicine across oncology, neurology, psychiatry, and cardiology. Founded in 2015 by Eric Lefkofsky (co-founder o

Schrödinger logo

Schrödinger

Life Sciences & BioTech
B2bGlobalPublicEnterpriseHealthtechAi PoweredSaasPlatformAnalytics

Schrödinger was founded in 1990 by Richard Friesner and David Pearlman in New York City, building physics-based computational methods for molecular simulation. For over 30 years the company has develo

Compare Be Biopharma with Competitors

Side-by-side AI visibility scores, platform breakdown, and market position.

For Be Biopharma

Claim This Profile

Are you from Be Biopharma? Claim your profile to see full AI mention excerpts, get weekly visibility change alerts, and optimize how AI systems describe your brand.

Claim Be Biopharma Profile →
For competitors & analysts

Track AI Visibility in Real Time

Monitor how ChatGPT, Gemini, Perplexity, and Claude mention Be Biopharma vs competitors. Get alerts when AI recommendations shift.

Start Free Tracking →