Formation Bio vs Tempus
Side-by-side comparison of AI visibility scores, market position, and capabilities
AI-Native Drug Development & Clinical Asset Acceleration
Formation Bio is an AI-native pharmaceutical company that acquires clinical-stage drug assets and accelerates their development to market using proprietary AI and operational technology; raised $372M in a 2024 Series D;
About
Formation Bio (formerly TrialSpark) is a New York-based AI-native pharmaceutical company founded in 2016 by Nicky Popp and Benjamine Liu. The company operates at the intersection of artificial intelligence and drug development, acquiring clinical-stage pharmaceutical assets — compounds that have demonstrated early safety and efficacy in human trials — and applying proprietary AI and operational technology to accelerate their development timelines and reduce costs. Rather than discovering new drug targets from scratch, Formation Bio's model focuses on execution excellence: identifying undervalued clinical assets and getting them to patients faster and more cheaply than traditional pharma development organizations can.
Publicly traded AI precision medicine company (Nasdaq: TEM); $1.27B revenue in 2025 (+83% YoY); $14B+ market cap; genomic profiling, algorithmic diagnostics, and clinical trial matching across oncology, neurology, and cardiology.
About
Tempus AI is a technology company applying artificial intelligence to advance precision medicine across oncology, neurology, psychiatry, and cardiology. Founded in 2015 by Eric Lefkofsky (co-founder of Groupon) and headquartered in Chicago, Illinois, Tempus built the world's largest library of clinical and molecular data and applies AI to help physicians make more personalized, data-driven treatment decisions. The company's core offerings include genomic profiling (sequencing tumor DNA to identify mutations and actionable targets), algorithmic diagnostic tests (AI-driven companion diagnostics for cancer treatment selection), clinical trial matching (connecting eligible patients to appropriate studies), and data licensing to pharmaceutical and biotech partners for drug discovery and clinical development.
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