Microbiotica

Emerging

Microbiotica raised $105M Series C in 2025 for its gut microbiome platform linking bacterial strains to disease, enabling live biotherapeutic products for cancer immunotherapy and IBD.

Microbiome Therapeutics
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Company Overview

About Microbiotica

Microbiotica applies genomics and machine learning to map the gut microbiome's causal role in disease, then develops live biotherapeutic products (LBPs) targeting the specific bacterial strains responsible. The company's Reference Microbiome database — built from thousands of patient samples — is the world's most comprehensive catalog of gut bacteria linked to disease outcomes, providing a systematic foundation for microbiome drug discovery.

Business Model & Competitive Advantage

Spun out of the Wellcome Sanger Institute in 2017, Microbiotica has demonstrated that specific microbiome compositions predict and mediate response to cancer immunotherapy (checkpoint inhibitors). Its lead programs aim to convert non-responders into responders by supplementing their microbiome with beneficial bacterial strains. Phase 1/2 trials in combination with anti-PD1 therapies are underway.

Competitive Landscape 2025–2026

The $105M Series C in 2025 will fund clinical advancement of Microbiotica's oncology and inflammatory bowel disease (IBD) programs. As the microbiome field matures from correlation to causation, Microbiotica's database advantage and clinical momentum position it as a leader in what could become a multi-billion dollar therapeutic category.

Revenue
$105M
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Key Differentiators

Emerging Innovator

Microbiotica is an emerging player bringing innovative solutions to the BioTech market.

Growth Stage

Microbiotica has achieved $105M in revenue, demonstrating strong product-market fit.

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