Twist Bioscience vs Restream
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Synthetic DNA manufacturing platform on silicon chips; $376M FY2025 revenue (+20% YoY). Supplies synthetic genes to 3,000+ customers across biotech, pharma, and AgBio.
About
Twist Bioscience was founded in 2013 in San Francisco by Emily Leproust, Bill Banyai, and Bill Peck, pioneering a silicon-based DNA synthesis platform that writes synthetic DNA at a fraction of the cost and error rate of conventional methods. By printing DNA on silicon wafers using a semiconductor-like process, Twist dramatically reduced the cost of synthetic genes from hundreds to single-digit dollars per gene, democratizing access to DNA writing for the life sciences.\n\nTwist serves over 3,000 customers across biopharmaceuticals, academic research, agriculture, and industrial biotechnology, offering synthetic genes, variant libraries, DNA data storage oligos, and antibody libraries for drug discovery. The company reported $376.6 million in FY2025 revenue, up 20% from $313 million in FY2024, driven by strong growth in its biopharma and drug discovery segments. Twist also operates a growing antibody drug discovery business, providing synthetic antibody libraries that power next-generation therapeutic discovery programs.\n\nTwist has a supply agreement with Ginkgo Bioworks for synthetic DNA to fuel Ginkgo's cell engineering platform, revised in 2025. The company is executing toward profitability, with improving gross margins as manufacturing scale increases. Its silicon-based DNA synthesis platform positions it as critical infrastructure for the emerging bioeconomy, synthetic biology, and DNA data storage industries.
Austin multi-streaming platform broadcasting live video to 30+ destinations including Twitch, YouTube, and Facebook Live simultaneously; trusted by creators, media companies, and businesses.
About
Restream is an Austin-based live streaming company that provides multi-stream broadcasting technology enabling content creators, businesses, and media companies to broadcast live video simultaneously to over 30 streaming destinations including Twitch, YouTube, Facebook Live, LinkedIn Live, and custom RTMP destinations from a single source. The platform eliminates the need to choose a single streaming platform by enabling simultaneous multi-destination broadcasting, maximizing audience reach across wherever viewers are watching. Restream also provides a browser-based live studio for creating professional broadcasts without dedicated streaming hardware, including overlays, lower-thirds, guest invitations, and screen sharing. The company serves a broad range of users from gaming streamers and podcasters to corporate communications teams running product launches and all-hands meetings. Founded in 2015 in Kyiv with operations in Austin, Restream has grown to serve millions of streamers globally. The company raised over $50M from investors including Bessemer Venture Partners and competes with StreamYard, OBS, and Wirecast in the live streaming software market.
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