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Dewpoint Therapeutics pioneers drug discovery targeting biomolecular condensates — liquid-like protein assemblies implicated in cancer, neurodegeneration, and metabolic disease; raised over $160M;
Dewpoint Therapeutics is a Boston-based biotechnology company founded in 2018 by Richard Young, Tony Hyman, and Clifford Brangwynne — three of the world's leading researchers in the science of biomolecular condensates. Condensates are dynamic, liquid-like assemblies of proteins and nucleic acids that form within cells through a process called phase separation. Dewpoint's thesis is that many diseases — including cancer, neurodegeneration, and metabolic disorders — involve the dysregulation of these condensates, and that drugs targeting condensate behavior represent a new class of therapies beyond conventional target-based drug discovery.
Karius raised $409M total including a $100M Series C in May 2024; its genomic blood test detects 1,000+ pathogens at 400+ U.S. hospitals; launched Karius Focus BAL for pneumonia in April 2025.
Karius is a Redwood City, CA-based life sciences company founded in 2014 that developed the Karius Test — a single blood draw that uses next-generation sequencing and AI to detect over 1,000 pathogens (bacteria, fungi, viruses, parasites) in seriously ill patients. The test is used when conventional cultures and targeted diagnostics fail, providing clinicians at transplant centers, children''s hospitals, and ICUs with a comprehensive pathogen report within 24 hours.
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