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Dewpoint Therapeutics pioneers drug discovery targeting biomolecular condensates — liquid-like protein assemblies implicated in cancer, neurodegeneration, and metabolic disease; raised over $160M;
Dewpoint Therapeutics is a Boston-based biotechnology company founded in 2018 by Richard Young, Tony Hyman, and Clifford Brangwynne — three of the world's leading researchers in the science of biomolecular condensates. Condensates are dynamic, liquid-like assemblies of proteins and nucleic acids that form within cells through a process called phase separation. Dewpoint's thesis is that many diseases — including cancer, neurodegeneration, and metabolic disorders — involve the dysregulation of these condensates, and that drugs targeting condensate behavior represent a new class of therapies beyond conventional target-based drug discovery.
AI protein design platform combining language models with lab automation; active learning cycles for enzyme, antibody, and therapeutic protein engineering optimization.
Cradle is a protein design platform using AI to help biotechnology and pharmaceutical companies engineer better proteins — enzymes, antibodies, and therapeutic proteins — with improved stability, activity, and manufacturability. Founded in 2021 and headquartered in Amsterdam with teams in San Francisco, Cradle raised approximately $24 million and targets biopharmaceutical, agricultural, and industrial biotechnology companies that need to engineer proteins with specific functional properties.
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