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Beckley Psytech (now AtaiBeckley) achieved FDA Breakthrough Therapy Designation for BPL-003 (5-MeO-DMT nasal spray) for treatment-resistant depression in October 2025; Phase 3 trial initiation planned Q2 2026.
Beckley Psytech is a UK-based clinical-stage biotechnology company developing psychedelic-derived medicines for neuropsychiatric disorders, with a primary focus on treatment-resistant depression (TRD). Its lead asset, BPL-003, is an intranasal formulation of 5-MeO-DMT (mebufotenin benzoate) designed to deliver a controlled, short-duration psychedelic experience under medical supervision. In July 2025, Beckley Psytech and its partner atai Life Sciences reported positive topline results from a Phase 2b trial of BPL-003, with a single 8mg dose achieving a 12.1-point reduction on standardized depression scales at day 29 — a clinically meaningful outcome.
Karius raised $409M total including a $100M Series C in May 2024; its genomic blood test detects 1,000+ pathogens at 400+ U.S. hospitals; launched Karius Focus BAL for pneumonia in April 2025.
Karius is a Redwood City, CA-based life sciences company founded in 2014 that developed the Karius Test — a single blood draw that uses next-generation sequencing and AI to detect over 1,000 pathogens (bacteria, fungi, viruses, parasites) in seriously ill patients. The test is used when conventional cultures and targeted diagnostics fail, providing clinicians at transplant centers, children''s hospitals, and ICUs with a comprehensive pathogen report within 24 hours.
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