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Beam Therapeutics develops precision genetic medicines using base editing technology that makes single-letter DNA changes without cutting the double helix.
Beam Therapeutics is a genetic medicines company founded in 2017 by base editing pioneers David Liu, J. Keith Joung, and Feng Zhang, having raised over $600M and gone public on Nasdaq. The company is built around base editing, a technology that makes precise single nucleotide changes in DNA without creating double-strand breaks, reducing the risk of unintended insertions or deletions compared to traditional CRISPR. Beam is developing a portfolio of base editing medicines targeting blood disorders, liver diseases, and immuno-oncology, including sickle cell disease, beta-thalassemia, and various cancers. The company also employs prime editing, a newer and even more precise gene editing modality for more complex genetic changes. Beam's pipeline includes both in vivo therapies delivered directly into the body and ex vivo cell therapy approaches where patient cells are edited outside the body and reinfused. As a clinical-stage company, Beam has programs in IND-enabling and Phase 1 trials and represents one of the most advanced next-generation gene editing platforms in development.
NASDAQ-listed (AAPL) world's most valuable company at $391B revenue with iPhone, Mac, and $25B+ App Store; Apple Intelligence AI and Vision Pro spatial computing competing across smartphones, PC, wearables, and services.
Apple Inc. is a Cupertino, California-based technology company — listed on NASDAQ (NASDAQ: AAPL) and the world's most valuable company by market capitalization at $3+ trillion — designing and manufacturing consumer electronics (iPhone, Mac, iPad, Apple Watch, AirPods, Apple Vision Pro), operating system software (iOS, macOS, watchOS, visionOS), and digital services (App Store, Apple Music, iCloud, Apple TV+, Apple Pay, Apple Arcade) through a vertically integrated hardware-software-services model that generates unparalleled ecosystem lock-in and customer loyalty. Founded by Steve Jobs, Steve Wozniak, and Ronald Wayne in 1976, Apple generated $391 billion in revenue in fiscal year 2024 with 66% iPhone contribution.
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