Tempus AI(TEM)

Challenger

AI precision medicine company. NASDAQ: TEM. 2025 revenue $1.27B (+83% YoY). World's largest clinical/molecular data library. Founded 2015, Chicago. 2026 guidance ~$1.59B.

Precision Medicine & Diagnostics
TEM
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Updated April 2026

Company Overview

About Tempus AI

Tempus AI is an AI-powered precision medicine company founded in 2015 by Eric Lefkofsky in Chicago, Illinois. The company has built the world's largest library of clinical and molecular data, comprising over 40 million research records including 1.5 million with matched clinical-genomic data. Tempus provides precision medicine services across oncology, cardiology, radiology, and depression through Genomics, Data and Services, and AI Applications product lines.

Business Model & Competitive Advantage

Tempus operates at the intersection of healthcare data and artificial intelligence, generating revenue from diagnostic testing, data licensing to pharmaceutical companies, and AI-powered clinical tools. Its xT genomic profiling platform helps oncologists identify targeted therapies and clinical trials. Tempus' data library is approximately 20 times the size of the Cancer Genome Atlas, giving it a significant competitive moat.

Competitive Landscape 2025–2026

Tempus went public on NASDAQ on June 14, 2024, under the ticker TEM. Full-year 2025 revenue reached $1.27 billion, up 83.4% YoY, with diagnostics revenue at ~$955 million. For 2026, Tempus guided approximately $1.59 billion in revenue with ~$65 million in adjusted EBITDA, signaling its path toward profitability.

Revenue
$1270M
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Key Differentiators

Strong Challenger

Tempus AI is an established challenger with significant market presence and competitive offerings in Healthcare Tech.

Enterprise Scale

With $1270M in revenue, Tempus AI operates at enterprise scale with proven market validation.

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