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Company Overview
About Tempus AI
Tempus AI is an AI-powered precision medicine company founded in 2015 by Eric Lefkofsky in Chicago, Illinois. The company has built the world's largest library of clinical and molecular data, comprising over 40 million research records including 1.5 million with matched clinical-genomic data. Tempus provides precision medicine services across oncology, cardiology, radiology, and depression through Genomics, Data and Services, and AI Applications product lines.
Business Model & Competitive Advantage
Tempus operates at the intersection of healthcare data and artificial intelligence, generating revenue from diagnostic testing, data licensing to pharmaceutical companies, and AI-powered clinical tools. Its xT genomic profiling platform helps oncologists identify targeted therapies and clinical trials. Tempus' data library is approximately 20 times the size of the Cancer Genome Atlas, giving it a significant competitive moat.
Competitive Landscape 2025–2026
Tempus went public on NASDAQ on June 14, 2024, under the ticker TEM. Full-year 2025 revenue reached $1.27 billion, up 83.4% YoY, with diagnostics revenue at ~$955 million. For 2026, Tempus guided approximately $1.59 billion in revenue with ~$65 million in adjusted EBITDA, signaling its path toward profitability.
Recent Activity
View all →Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine, today announced a new initiative with Bristol Myers Squibb (NYSE: BMY). This collaboration aims to leverage AI, multimodal real-world data and data science techniques to optimize clinical trial designs and enhance the Probability of Technical & Regulatory Success … Continued The post Tempus Expands Strategic Collaboration with Bristol Myers Squibb to Enhance the Probability of Success Across Clinical Development Programs In Oncology and Neuroscience appeared first on Tempus .
Material Event filed 2026-05-13
The post From recurrence monitoring to treatment response: MRD data insights across the cancer care continuum appeared first on Tempus .
CHICAGO, May 5, 2026 — Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine and patient care, today reported financial results for the quarter ended March 31, 2026. Revenue of $348.1 million, up 36.1% year-over-year Diagnostics revenue of $261.1 million, representing 34.7% growth year-over-year, driven by Oncology … Continued The post Tempus Reports First Quarter 2026 Results appeared first on Tempus .
Material Event filed 2026-05-05
Quarterly Report filed 2026-05-05
The path to bringing novel therapies to market is challenged by high attrition rates and the increasing complexity of patient biology. Foundation models offer a new approach to addressing challenges in drug development, particularly when trained on diverse multimodal, de-identified real-world data. In a recent webinar, Tempus leaders Razik Yousfi, SVP and GM of AI … Continued The post Q&A: From proof of concept to clinical deployment: How foundation models are accelerating drug development appeared first on Tempus .
Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine, today announced that the company will host an Investor Day on Friday, May 29, 2026. The event will start at 8:00 a.m. CT / 9:00 a.m. ET and will feature Tempus’ leadership team, including, Founder and CEO Eric … Continued The post Tempus to Host Inaugural Investor Day on May 29, 2026 appeared first on Tempus .
As therapies become more targeted, the central challenges of drug development have intensified. Trial protocols are more complex, and finding the right patients for biomarker-driven studies is increasingly difficult, leading to costly enrollment delays and high failure rates.1, 2 At Tempus, we believe the solution is not just a better process, but a fundamentally new … Continued The post Designing smarter trials: A new model for clinical development appeared first on Tempus .
Tempus AI, Inc. (NASDAQ: TEM), a technology company advancing precision medicine through the practical application of artificial intelligence, today announced it has been named to TIME’s 10 Most Influential Health and Life Science Companies of 2026. This inaugural TIME100 Companies: Industry Leaders list, an expansion of the TIME100 Most Influential Companies issue, recognizes the organizations … Continued The post Tempus Named to TIME’s 10 Most Influential Health and Life Science Companies of 2026 appeared first on Tempus .
Objectives Mirvetuximab soravtansine (MIRV), a first-in-class folate receptor alpha (FRα) targeted antibody-drug conjugate (ADC), demonstrated a survival benefit over chemotherapy in the phase III MIRASOL study. To date, no study has evaluated downstream biomarkers that may modulate response which may occur at multiple steps of the ADC pathway. Here, we investigated genomic and transcriptomic alterations … Continued The post Genomic and Transcriptomic Analysis To Uncover Potential Biomarkers of Response and Primary Resistance to Mirvetuximab Soravtansine in Patients With Ovarian Cancer appeared first on Tempus .
Objectives The glycoprotein MUC16 is cleaved to form serum CA125, an established biomarker in endometrial cancer. First-generation MUC16 antibody-drug conjugates (ADCs) were thought to have sub-optimal tumor penetration, in part, because their targeting antibodies were specific for the cleaved portion of CA125 and bound it in serum, creating an antigen sink. Improvements in ADCs—such as … Continued The post High and Stable MUC16 Expression in Endometrial Cancer Highlights Potential for Targeted Antibody-Drug Conjugate Development appeared first on Tempus .
Key Differentiators
Strong Challenger
Tempus AI is an established challenger with significant market presence and competitive offerings in Healthcare Tech.
Enterprise Scale
With $1.27B in revenue, Tempus AI operates at enterprise scale with proven market validation.
Frequently Asked Questions
Estimated Visibility Trend (Beta)
Simulated 8-week rolling score
Based on estimated brand signals. Historical tracking coming soon.
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