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Pacific Biosciences

Growth

Pioneer of single-molecule real-time (SMRT) long-read sequencing; Revio system targets clinical and research markets. Guides to $150–$170M FY2025 revenue with 40%+ gross margins.

Best for: Long-Read Sequencing
22
AI Score
Grade D↑ Trending
AI Visibility Score (Beta)
Life Sciences & BioTechLong-Read SequencingWebsiteUpdated April 2026

Brand Intelligence Graph

Company Overview

About Pacific Biosciences

Pacific Biosciences (PacBio) was founded in 2004 in Menlo Park, California and pioneered single-molecule real-time (SMRT) sequencing technology, enabling long-read DNA sequencing that can span tens of thousands of base pairs per read. This capability is essential for resolving complex genomic regions—structural variants, repeat expansions, methylation patterns, and full-length transcripts—that short-read platforms like Illumina cannot accurately assemble.

Business Model & Competitive Advantage

PacBio's Revio system, launched in 2023, offers a dramatic improvement in throughput and cost efficiency over prior instruments, targeting both research and clinical sequencing laboratories. Key applications include rare disease diagnosis, pharmacogenomics, plant and animal genomics, and clinical oncology. The company guides to $150–$170 million in FY2025 revenue with gross margins exceeding 40% and a path to cash flow breakeven by 2027.

Competitive Landscape 2025–2026

PacBio competes primarily with Oxford Nanopore Technologies in the long-read segment, together driving adoption of long-read sequencing for comprehensive genome assembly and clinical applications. The company is expanding its high-accuracy (HiFi) chemistry and developing Onso, a short-read system, to capture a broader share of the sequencing market. With approximately $260 million in cash, PacBio is well-positioned to scale its clinical business.

Founded
2004
Revenue
$170M
Curated content • Fact-checked and verified

Key Differentiators

Growth Stage

Pacific Biosciences has achieved $170M in revenue, demonstrating strong product-market fit.

Frequently Asked Questions

Estimated Visibility Trend (Beta)

Simulated 8-week rolling score

22
↑ Trending

Based on estimated brand signals. Historical tracking coming soon.

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