Company Overview
About Life Biosciences
Life Biosciences is running the first FDA-cleared human trial of partial epigenetic reprogramming, using gene therapy to reverse vision loss caused by aging. Co-founded by Harvard aging biologist David Sinclair — whose research showed that aged retinal cells could be restored to youthful function by expressing Yamanaka factors — Life Biosciences received FDA clearance for its IND (Investigational New Drug) for ER-100 in optic neuropathies in January 2026 and closed an $80 million Series D in April 2026.
Business Model & Competitive Advantage
The optic neuropathy indication is a smart clinical strategy: the eye is an immune-privileged site that allows targeted gene therapy delivery with minimal systemic risk, enabling safety data to be collected in a setting where the target tissue and disease are well-characterized. Positive safety and efficacy data in the eye would establish proof-of-concept for epigenetic reprogramming in vivo, enabling the approach to be extended to systemic aging across other tissues.
Competitive Landscape 2025–2026
The $80 million Series D provides runway through trial completion and positions Life Biosciences as the first company to generate human clinical data on whether the epigenetic clock of aging can be reversed — a question with transformative implications for medicine if the answer is yes.
Open Positions
Reddit Discussions
Key Differentiators
Emerging Innovator
Life Biosciences is an emerging player bringing innovative solutions to the BioTech market.
Frequently Asked Questions
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