Illuminant Surgical logo

Illuminant Surgical

Emerging

Medical device company projecting CT/MRI anatomy directly onto patients during surgery for real-time guidance; YC-backed $500K raised at $750K-$900K revenue with SIGGRAPH 2025 research presentation.

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HealthcareWebsiteUpdated March 2026

Company Overview

About Illuminant Surgical

Illuminant Surgical is a medical device company developing Skylight — a real-time anatomical projection system that displays medical imaging data (CT scans, MRI, ultrasound) directly onto the patient's body surface during surgery, giving surgeons continuous visual guidance about subsurface anatomy without looking away from the operative field. Founded in 2022 and backed by Y Combinator with $500,000+ raised from YC, the US National Science Foundation, and angel investors, Illuminant generated $750,000-$900,000 in revenue in 2024 with an 18-person team and presented Skylight research at SIGGRAPH 2025.

Business Model & Competitive Advantage

Skylight's projection mapping technology solves a persistent surgical navigation problem: surgeons currently navigate by mentally integrating preoperative scans with the operative anatomy, requiring constant mental translation between imaging and patient orientation. Skylight registers preoperative CT/MRI data to the patient's surface in the operating room and projects anatomical landmarks, critical structures, and surgical boundaries directly onto the skin — providing continuous anatomical awareness without head-mounted displays, monitor glances, or robotic arm manipulation. Unlike navigation systems that require fiducial markers or intraoperative CT, Skylight's optical projection approach maintains the direct line of sight surgeons depend on. The SIGGRAPH 2025 presentation reflects the computer vision and geometric registration algorithms underlying the real-time projection mapping.

Competitive Landscape 2025–2026

In 2025, Illuminant Surgical competes in the surgical navigation market with Stryker's Mako robotic navigation, Medtronic StealthStation, and optical navigation systems (Brainlab, Fiagon) for surgical guidance technology adoption. Traditional surgical navigation requires expensive capital equipment (robotic arms, navigation towers) with complex setup workflows — Skylight's projector-based approach positions as a lower-cost, faster-setup augmented reality navigation alternative. Y Combinator backing provides credibility with the Silicon Valley surgical robotics community. The 2025 strategy focuses on FDA 510(k) clearance for the Skylight system, expanding clinical validation studies across multiple surgical specialties (orthopedic, spine, general surgery), and building partnerships with hospital systems seeking navigation technology at lower cost and setup complexity than robotic alternatives.

Founded
2022
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Key Differentiators

Emerging Innovator

Illuminant Surgical is an emerging player bringing innovative solutions to the Healthcare market.

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