Biocogniv

Emerging

FDA Breakthrough Device-designated AI platform predicting sepsis mortality risk in emergency departments; $17.08M from Breyer Capital and YC generating $2.6M revenue at 13-person Burlington-based team.

Updated March 2026

Company Overview

About Biocogniv

Biocogniv is a Burlington, Vermont-based clinical AI company that has developed an FDA Breakthrough Device Designation-granted platform for predicting sepsis-related mortality and ICU admission risk in emergency departments — using AI analysis of routine clinical data (vital signs, lab values, patient history) to identify patients at highest risk of deterioration hours before clinical signs become obvious to clinicians, enabling earlier intervention in one of healthcare's most time-sensitive conditions. Founded in 2019 and a Y Combinator W20 graduate, Biocogniv raised $17.08 million from Breyer Capital and YC, generating $2.6 million in revenue in 2024 with a 13-person team.

Business Model & Competitive Advantage

Biocogniv's algorithm analyzes the data already being collected in emergency departments — EHR data, nursing assessments, vital signs monitoring, laboratory results — to generate a continuous risk score that predicts which patients will develop sepsis-related complications requiring ICU admission within the next 6-12 hours. Unlike single-timepoint scoring systems (like SOFA or SIRS criteria), Biocogniv's model incorporates the trajectory of clinical data over time, enabling earlier detection of the subtle patterns that precede septic shock.

Competitive Landscape 2025–2026

In 2025, Biocogniv competes in the AI clinical decision support and sepsis detection market with Sepsis-prediction tools from Epic (Deterioration Index, built into Epic EHR), IBM Watson Health (Micromedex), and Philips (IntelliVue Guardian) for sepsis risk monitoring in acute care. Sepsis kills 270,000+ Americans annually and is the leading cause of in-hospital mortality — earlier detection and intervention directly reduces mortality. The FDA Breakthrough Device Designation accelerates the regulatory pathway and signals clinical significance. Breyer Capital's investment (known for healthcare technology) provides both capital and strategic credibility. The 2025 strategy focuses on expanding hospital contracts, completing the FDA clearance process to enable broader commercial deployment, and building the EHR integration partnerships with Epic and Cerner that scale adoption beyond manual API connections.

Revenue
$17.08M
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Key Differentiators

Emerging Innovator

Biocogniv is an emerging player bringing innovative solutions to the Healthcare market.

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