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Verve Therapeutics develops single-course gene editing medicines for cardiovascular disease, aiming to permanently lower LDL cholesterol with one treatment.
Verve Therapeutics is a clinical-stage genetic medicines company founded in 2018 by Andrew Bellinger and Sekar Kathiresan, focused exclusively on using base editing to treat cardiovascular disease. The company is developing one-time treatments that permanently lower LDL cholesterol and triglycerides by editing genes in liver cells that regulate lipid metabolism, including PCSK9 and ANGPTL3. Verve's approach targets the root cause of common cardiovascular disease rather than requiring lifelong daily medication, with the goal of a single infusion delivering durable benefit. The lead program VERVE-101 targets PCSK9 in liver cells and has entered Phase 1b clinical trials, with early data showing substantial and durable LDL reductions in patients with heterozygous familial hypercholesterolemia. Verve is publicly traded on Nasdaq and has established partnerships with Vertex Pharmaceuticals to advance the cardiovascular base editing pipeline. The company represents a fundamentally new approach to preventing heart attacks and strokes at the genetic level.
Raised $115M (Feb 2026) led by General Atlantic. Post-merger with Soli Organic creates largest indoor farm in North America. ~$200M combined first-year revenues.
80 Acres Farms is a commercial-scale indoor vertical farming company that, following its merger with Soli Organic, operates the largest indoor farming network in North America. The company raised $115 million in February 2026 led by General Atlantic, with projected first-year combined revenues approaching $200 million — making it one of the few vertical farming companies to achieve genuine commercial scale after years of industry attrition that eliminated several high-profile competitors.
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