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Sana Biotechnology develops engineered cell and gene therapies with fusogen delivery technology to treat serious diseases through in vivo and ex vivo approaches.
Sana Biotechnology is a publicly traded gene therapy company founded in 2018 by veterans of Juno Therapeutics and other leading cell therapy companies. The company is building technologies to repair or replace any gene in any cell, with a particular focus on its proprietary fusogen-based delivery platform that enables engineered cells to fuse with and deliver genetic material to specific target cells in the body. This approach could enable off-the-shelf cell therapies and in vivo gene editing without the need to harvest and engineer patient cells individually. Sana has programs targeting blood cancers, autoimmune diseases, and type 1 diabetes, exploring both in vivo gene delivery and ex vivo engineered cell therapies. The company went public through an IPO in 2021, raising substantial capital to advance its novel platform. Sana has formed research collaborations with academic institutions and pharmaceutical companies to advance specific programs. The company represents the cutting edge of cell and gene therapy with proprietary delivery technologies that could unlock new therapeutic approaches beyond what current viral vector and CRISPR systems enable.
NYSE: SHOP e-commerce platform at $8.88B FY2024 revenue with $292.28B GMV across 4.82M stores; Black Friday $11.5B processing competing with WooCommerce and BigCommerce for small-to-enterprise direct-to-consumer commerce.
Shopify Inc. is an Ottawa, Canada-based e-commerce platform — listed on NYSE (NYSE: SHOP) — providing 4.82+ million active merchant stores of all sizes (from solo entrepreneurs to enterprise brands) with tools for online store creation, multi-channel selling (web, mobile, social, in-person), payment processing (Shopify Payments, Shop Pay), inventory management, fulfillment, and marketing analytics, generating $8.88 billion in revenue in fiscal year 2024 (+26% year-over-year) with $292.28 billion in gross merchandise volume (GMV, +24%) and 875+ million customers who have purchased from Shopify merchant stores. Founded in 2006 by Tobias Lütke, Daniel Weinand, and Scott Lake (started as a snowboard equipment store, pivoted to become the platform), Shopify has become the operating system for independent commerce — the default e-commerce infrastructure for the direct-to-consumer brand economy.
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