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This is the official mobile app to be used for Amgen events. Attendees will have the ability to stay connected during the entire event. Features include being able to view your personalized schedules,

Download the Amgen Fitness Center App today! From this mobile App you can view class schedules, sign-up for classes, as well as view the studio’s location information. Optimize your time and maximize 

The Amgen 20240113 app is intended for use to collect patient reported outcomes relating to a clinical trial. Patients must be given accounts by a participating site in order to log in to the app.

A FreeCAD module that uses Generative Design to design optimally for Additive Manufacturing

AMGeneration

command line tool for frequent amaranth HDL tasks (generate sources, show design)

amgen

The basis of this project involves analyzing Amgen future profitability based on its current business environment and financial performance. Technical Analysis, on the other hand, includes reading the charts and using statistical figures to identify the trends in the stock market. The dataset used for this analysis was downloaded from Yahoo finance for year 2009 to 2019. There are multiple variables in the dataset – date, open, high, low, volume. Adjusted close. The columns Open and Close represent the starting and final price at which the stock is traded on a day. High and Low represent the maximum, minimum price of the share for the day. The profit or loss calculation is usually determined by the closing price of a stock for the day, I used the adjusted closing price as the target variable. I downloaded data on the inflation rate, unemployment rate, Industrial Production Index, Consumer Price Index for All Urban Consumers: All Items and Real Gross Domestic Product as independent variables, Quarterly Financial Report: U.S. Corporations: Cash Dividends Charged to Retained Earnings All Manufacturing: All Nondurable Manufacturing: Chemicals: Pharmaceuticals and Medicines Industry, Producer Price Index by Industry: Pharmaceutical Preparation Manufacturing, 30-Year Treasury Constant Maturity Rate, and Producer Price Index by Industry: Pharmaceutical and Medicine Manufacturing Index.  The independent variables are economic parameters which was obtained from Federal Reserve Economic Data (FRED) website.  Methodology  1. Linear Regression: The linear regression model returns an equation that determines the relationship between the independent variables and the dependent variable. I used linear regression tool in Alteryx with ARIMA tool to forecast the stock prices for the year. The algorithm was trained with the historical data to see how the variables impact on the dependent variable. The test data was used to predict the adjusted closing price for the year and predicted a stock price of $193.38.  2. Support Vector Machines (SVM): Support Vector Networks (SVN), are a popular set of supervised learning algorithms originally developed for classification (categorical target) problems and can be used for regression (numerical target) problems. SVMs are memory efficient and can address many predictor variables. This model finds the best equation of one predictor, a plane (two predictors) or a hyperplane (three or more predictors) that maximally separates the groups of records, based on a measure of distance into different groups based on the target variable. A kernel function provides the measure of distance that causes to records to be placed in the same or different groups and involves taking a function of the predictor variables to define the distance metric. I used the SVM tool in Alteryx with ARIMA tool to forecast the stock prices for the year and predicted a stock price of $189.44.  3. Spline Model: The Spline Model tool was used because it provides the multivariate adaptive regression splines (or MARS) algorithm of Friedman. This statistical learning model self-determines which subset of fields best predict a target field of interest and can capture highly nonlinear relationships and interactions between fields. I used the Spline tool in Alteryx with ARIMA tool to forecast the stock prices for the year and predicted a stock price of $201.84.  The results from the models was weighted by comparing the RMSE of each model. A lower RMSE indicates that the model’s predictions were closer to the actual values. However, a simpler model with the same RMSE as a more complex model is generally better, as simpler models are less likely to be overfit. Though the Spline model had a lower RMSE, the Linear Regression model had fewer variables. Thus, we combined the 3 models with the ARIMA forecast in a model ensemble, which allows us to use the results of multiple models. The forecasted stock price is $197.99 with 1.5% increase for 31st December 2019. Apart from economic parameters, stock price is affected by the news about the company and other factors like demonetization or merger/demerger of the companies. There are certain intangible factors which can often be impossible to predict beforehand hence the model predicts that the stock price of Amgen will continue to rise except there is a drastic downturn of the company. 

Ensemble-Predictive-Model-Forecasting-AMGEN-stock-price-at-year-end-31s

Created to show work done in prep for an interview

AmgenInterview

amgen2013

Amgen publishes failures to replicate high-profile science

How Amgen Lost the PCSK9 Patent War

Salesforce, Honeywell, Amgen into the Dow; Exxon, Raytheon, and Pfizer Out

New Once/Month Drug Causes 20 Percent Weight Loss in Early Amgen Results

Amgen says its cholesterol shot prevented heart problems in a broad population

Amgen Inc. is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. The company is ranked 18th on the list of largest biomedical companies by revenue. The name "AMGen" is a portmanteau of the company's original name, Applied Molecular Genetics. The company's major products are Prolia and XGEVA for treatment of osteoporosis and bone diseases, Enbrel for treatment of autoimmune diseases, Repatha for treatment of hyperlipidemia, Otezla for treatment of psoriasis and psoriatic arthritis, Tepezza to treat Graves' ophthalmopathy, Evenity to treat osteoporosis, Kyprolis to treat cancer, Nplate to regulate platelet production, and Aranesp to stimulate erythropoiesis. Amgen has 17 clinical programs underway in Phase III, eight in Phase II, and 19 in Phase I. Its pipeline includes MariTide, an anti-obesity medication administered once per month by injection.

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