Turn Biotechnologies

Emerging

Raised $29M Series A. Acquired ARMMs vesicular delivery tech (Mar 2025). Delivers mRNA cocktails that transiently reprogram aged cells to youthful epigenetic states without altering DNA.

mRNA Epigenetic Reprogramming
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Updated April 2026

Company Overview

About Turn Biotechnologies

Turn Biotechnologies is a longevity company using modified mRNA cocktails to transiently reprogram aged cells back toward a youthful epigenetic state — without permanently altering DNA sequences. The company has raised $29 million in Series A financing and acquired ARMMs (Arrestin Domain-Containing Protein 1 Mediated Microvesicle) technology in March 2025 to significantly upgrade the delivery capability of its mRNA reprogramming platform.

Business Model & Competitive Advantage

The mRNA reprogramming approach is designed to be reversible and transient: unlike CRISPR or viral gene therapies that make permanent changes to DNA, Turn's mRNA molecules naturally degrade after delivering their cellular reprogramming instructions. This potentially safer profile addresses one of the primary clinical concerns with epigenetic reprogramming approaches — the risk that partial reprogramming might induce inappropriate cell state changes that persist.

Competitive Landscape 2025–2026

Turn's dermatology beachhead — applying mRNA reprogramming to aged skin cells to demonstrate in vivo rejuvenation before advancing to systemic conditions — is a clinically accessible first proof point. Skin is directly observable, has established outcome metrics, and allows safety assessment without the systemic monitoring required for internal tissue reprogramming. The ARMMs acquisition significantly upgrades the mRNA delivery system, improving cellular uptake and reducing immune response to the delivery vehicle.

Revenue
$29M
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Key Differentiators

Emerging Innovator

Turn Biotechnologies is an emerging player bringing innovative solutions to the BioTech market.

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