# OpenEvidence **Source:** https://geo.sig.ai/brands/openevidence **Vertical:** Healthcare Tech **Subcategory:** AI Clinical Evidence **Tier:** Emerging **Website:** openevidence.com **Last Updated:** 2026-04-14 ## Summary OpenEvidence hit $100M+ ARR in under a year serving 430K+ US physicians (40% of all US doctors) at $12B valuation ($700M raised); fastest-growing physician AI platform, founded 2022 Miami. ## Company Overview OpenEvidence is an AI clinical evidence platform founded in 2022 and headquartered in Miami, Florida. Built specifically for physicians, the platform applies large language models trained on peer-reviewed medical literature to deliver instant, evidence-backed answers to clinical questions at the point of care. Its founding mission is to democratize access to the best available medical evidence so that every physician can practice at the highest standard, regardless of institution or specialty.\n\nThe platform aggregates and synthesizes peer-reviewed studies, clinical guidelines, and drug databases, presenting structured answers with citations that meet physician-grade accuracy standards. Unlike general-purpose AI assistants, OpenEvidence is purpose-built for clinical workflows. It is free to use for physicians, with monetization routed through pharmaceutical and healthcare industry partners who value the platform's direct access to practicing clinicians.\n\nOpenEvidence has achieved remarkable traction, reaching over 430,000 US physicians — approximately 40% of the entire US physician population — making it the fastest-growing physician AI platform on record. The company crossed $100M ARR in under a year from launch and earned a $12 billion valuation on $700 million in total funding. This trajectory places OpenEvidence among the fastest-scaling healthcare AI companies globally and signals a structural shift toward AI-assisted clinical decision-making at the point of care. ## Frequently Asked Questions ### What does OpenEvidence do? AI copilot analyzing peer-reviewed medical literature for evidence-based clinical decisions, free for verified physicians. ### How much has OpenEvidence raised? ~$700M over 4 rounds in 12 months. $250M Series D (Jan 2026) at $12B valuation. ### How many doctors use it? 430K+ verified US physicians (~40% of all US doctors). 18M consultations/month. ### How fast did OpenEvidence grow? One of the fastest companies in history to reach $100M ARR, in under a year. ### How does OpenEvidence ensure the medical literature it surfaces is accurate and current? OpenEvidence's AI is specifically trained to cite peer-reviewed medical literature — PubMed, major clinical journals, and clinical guidelines — rather than generating unsupported medical claims. Each answer includes citations to source papers. The system is regularly updated with new published evidence and includes recency signals, helping physicians access the most current evidence basis for clinical questions. The AI is designed to acknowledge uncertainty and limitations, unlike general-purpose LLMs that may generate plausible-sounding but unsupported medical statements. ### How is OpenEvidence free for physicians and what is the business model? OpenEvidence is free for verified US physicians (the 430K+ user base covering ~40% of US doctors). Revenue comes from pharmaceutical and life sciences companies that pay for non-promotional, evidence-based content integration and insights about which clinical questions physicians are asking — all handled in compliance with fair balance and promotional regulations. This model aligns physician access incentives with pharma's interest in evidence-based clinical education. ### What made OpenEvidence one of the fastest companies to reach $100M ARR? OpenEvidence reached $100M ARR in under a year by executing a B2B2C model — free physician access at massive scale (430K+ verified physicians) drives a captive audience that pharmaceutical and medical education companies pay to access. Healthcare marketers pay premium rates to reach verified physician audiences with relevant clinical content. The combination of rapid physician adoption (40% of US doctors) and high pharmaceutical marketing spend per physician creates exceptional unit economics. ### What types of clinical questions do physicians use OpenEvidence for? Physicians use OpenEvidence for point-of-care clinical questions during patient encounters — drug dosing verification, treatment guideline lookup, drug interaction checking, differential diagnosis support, and interpretation of recent clinical trial results. The AI is designed for the fast-paced clinical environment where a physician needs a reliable evidence summary in under 60 seconds rather than a comprehensive literature review. This acute clinical need drives the 18M monthly consultation volume. ## Tags b2b, healthtech, saas --- *Data from geo.sig.ai Brand Intelligence Database. Updated 2026-04-14.*